Freederm Gel 25g Freederm Gel 25g Freederm Gel is a medicinal treatment for mild to moderate inflammatory acne, including inflamed pimples and spots. It contains nicotinamide, an anti-inflammatory active ingredient that helps reduce the swelling, redness and tenderness associated with inflamed acne. The lightweight, fragrance-free gel can be applied to affected areas of the face, back and chest and is suitable for adults, children and the elderly.